Metaxalone is a muscle relaxant that is used to mitigate pain that occurs as a result of strains and sprains and a range of other musculoskeletal conditions. Metaxalone is marketed by King Pharmaceuticals under the brand name Skelaxin.
Skelaxin works by inhibiting the impulses of the nerves (the feelings of pain) to the brain. Metaxalone is generally regarded as a muscle relaxant that is temperate in strength. The chances of one developing side effects as a result of Metaxalone are very low.
The side effects of Metaxalone include nausea, loss of appetite, stomach aches, low fever, dark colour in stools, dark colour in urine, and jaundice. Other side effects, which are far less serious, include drowsiness and dizziness, nervousness, anxiety and feeling irritable, headaches, vomiting, mild nausea, stomach upsets, and skin rashes.
Cyclobenzaprine is a muscle relaxant—a drug taken for the relief of musculoskeletal spasms and the pains that come with them as well as other musculoskeletal conditions. Cyclobenzaprine is marketed under various brand names, most notably Flexeril.
Cyclobenzaprine has undergone more in-depth studies than other drugs similar to it (for example Skelaxin). Cyclobenzaprine also has off-label uses such as for the treatment of fibromyalgia. Cyclobenzaprine is also being studied and developed for the management of fibromyalgia syndrome.
Muscle spasms usually afflict one who has sustained an injury of some sort. These spasms come about so as to provide stability to the injured body part and in turn prevent any more damage from occurring. Muscle spasms are very painful, hence the need to treat them. Cyclobenzaprine is used to treat muscle spasms (it is approved by the FDA for that) that are bracketed together with brutally agonizing musculoskeletal conditions. It peaks in the first couple of days of administering the medication and relieves the pain in all of two weeks. After that time, there are no known benefits of the drug. For this reason, Cyclobenzaprine therapy cannot be done in the longer term.
Cyclobenzaprine also does virtually nothing to cure spasms that occur as a result of cerebral palsy and other such conditions.
Side effects of Cyclobenzaprine include dizziness, drowsiness, constipation and/or tiredness.
The conclusion is that both these drugs are muscle relaxants that work pretty much the same way and are dependent on the dosages they are administered in.
Their side effects are similar too. It is hard for one who is not a medical practitioner to discern the two drugs down to the very last detail. Doctors will prescribe whichever they think is best since they are very similar.